Regarding taking two tylenol & some alcohol: YOU SHOULD BE SAFE.
The below is from epocrates, probably the most-used medical program by providers. Also a journal review.
1.it describes that the dosage for mild pain or fever is 325-1000 mg PO (by mouth) q4-6h (every 4-6 hours) I don’t think u did more than these.
2.hepatic dysfunction – don’t use or at least decrease the dose, or just use another pain med, but I assume u don’t already have liver failure.
3.according to one doctor with 20 yrs of experience I bounce ideas off, u don’t want to do more than 4,000 mg per day & over 10,000 mg per day would be hepatotoxic, toxic to the liver. I doubt u took either of these doses.
4.the liver is effected by tylenol, & alcohol. When I was studying for one set of boards, one joke to remember AST, a liver enzyme used to evaluate liver function, is to remember A= alcohol, S= statins ant T= tylenol. So, yes, u do not want to take them for a long period of time as it can effect ur liver. I don’t remember where I heard it from, but the idea that u need to do something about the pain if u r using ibuprofen over twice per week may be a good rule for tylenol also
5.It appears that instead of alcohol & tylenol combined together being worse for ur liver, a single dose of alcohol actually protects the liver from the damages of toxic dose, as listed below.
6.The other journal below describes that an increased therapeutic use of Tylenol while fasting or routinely drinking alcohol can cause acute liver failure. There is risks to any drug, they r not harmless, even something as innocent as tylenol
Tylenol / acetaminophen
Adult Dosing- Dosage forms: 325,500; 160/5 mL
Pain, mild - [325-1000 mg PO q4-6h]
Max: 1 g/dose, 4 g/24h
Fever - [325-1000 mg PO q4-6h]
Max: 1 g/dose, 4 g/24h
Hepatic dosing - [not defined]
Hepatic impairment: consider decr. dose
The apparent protective effects of alcohol if taking a hepatotoxic dose of Tylenol:
Toxicology & Applied Pharmacology
Volume 100, Issue 3, 15 September 1989, Pages 391-397
http://sciencedirect.com/science?_ob=ArticleURL&_udi=B6WXH-4DDNMH9-DC&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=1df3b7f995d3e4fca0468a2ad4429493
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Acetaminophen hepatotoxicity: An update
JournalCurrent Gastroenterology Reports
PublisherCurrent Medicine Group LLC
ISSN1522-8037 (Print) 1534-312X (Online)
IssueVolume 1, Number 1 / February, 1999
DOI10.1007/s11894-999-0086-3
Pages42-49
A second pattern of liver toxicity, frequently seen in the United States, occurs due to a therapeutic misadventure with the drug [1,2••]. These patients often r regular alcohol users or have been fasting, & they r taking acetaminophen to relieve pain. They typically present to the hospital with severe liver failure 3 to 4 days after
consumption of the acetaminophen